The healthcare provider orders Lasix 40 mg IV now. The concentration available is Lasix 20 mg/mL. How many mL will the patient receive?

Choice A reason: To calculate the volume, divide the ordered dose (8 mg) by the concentration (5 mg/mL): 8 ÷ 5 = 1.6 mL. Choice A (1.4 mL) underestimates the volume, delivering only 7 mg (1.4 × 5), which is insufficient for the prescribed dose, making it incorrect for accurate medication administration.

Choice B reason: Calculating 8 mg ÷ 5 mg/mL yields 1.6 mL. Choice B (1.8 mL) would deliver 9 mg (1.8 × 5), exceeding the ordered dose. This overdose could increase the risk of sedation or respiratory depression, as Valium (diazepam) is a benzodiazepine with potent CNS effects, making this choice incorrect.

Choice C reason: The correct volume is 8 mg ÷ 5 mg/mL = 1.6 mL. Choice C (1.2 mL) delivers only 6 mg (1.2 × 5), which is below the prescribed dose. This underdose could result in inadequate therapeutic effects, such as insufficient anxiety relief or seizure control, making it an incorrect choice.

Choice D reason: Dividing the ordered dose (8 mg) by the concentration (5 mg/mL) gives 8 ÷ 5 = 1.6 mL. This volume accurately delivers the prescribed 8 mg of Valium, ensuring therapeutic efficacy for conditions like anxiety or seizures while minimizing risks of over- or under-dosing, making it the correct choice.

Choice A reason: NSAIDs, like ibuprofen, exacerbate peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD) by inhibiting COX-1, reducing protective gastric mucus and increasing acid-related damage. They are contraindicated in these conditions, making this choice incorrect for treatment.

Choice B reason: Antacids neutralize gastric acid, providing rapid symptom relief in PUD and GERD by reducing acid irritation on the esophagus and stomach lining. They are a standard, non-prescription option for mild symptoms, making this a correct choice for managing these conditions.

Choice C reason: Laxatives treat constipation by promoting bowel movements but have no role in PUD or GERD, which involve acid-related damage to the stomach or esophagus. They don’t affect gastric acid or mucosal protection, making this choice incorrect for treatment.

Choice D reason: H2 antagonists, like ranitidine, reduce gastric acid secretion by blocking histamine receptors on parietal cells, promoting ulcer healing and relieving GERD symptoms. They are a mainstay treatment for both conditions, making this a correct choice for effective management.

Choice E reason: Proton pump inhibitors, like omeprazole, strongly inhibit gastric acid production by blocking the proton pump in parietal cells, allowing ulcer healing and reducing GERD symptoms. They are first-line therapy for PUD and GERD, making this a correct choice.