The nurse administers a drug to a patient whose heart rate is bradycardic aimed at increasing heart rate and myocardial activity. What adrenergic receptor is this drug stimulating?
Beta 1
Beta 2
Alpha 2
Alpha 1
The Correct Answer is A
A) Beta 1: Beta-1 adrenergic receptors are primarily located in the heart and are responsible for increasing heart rate (chronotropy), the force of contraction (inotropy), and the conduction speed of electrical impulses within the heart (dromotropy). When a drug is given to increase heart rate and myocardial activity, it is stimulating the beta-1 receptors, which enhance the heart's performance..
B) Beta 2: Beta-2 receptors are predominantly found in smooth muscles, such as those
in the bronchi, blood vessels, and uterus. Stimulation of beta-2 receptors leads to relaxation of these muscles, including bronchodilation and vasodilation, which would not have a direct effect on increasing heart rate or myocardial activity.
C) Alpha 2: Alpha-2 receptors are primarily located in the central nervous system (CNS) and act to inhibit the release of norepinephrine, leading to a reduction in sympathetic nervous system activity. They have the opposite effect of what is desired in this case, as stimulation of alpha-2 receptors would actually lower heart rate and decrease myocardial activity, not increase it.
D) Alpha 1: Alpha-1 receptors are found in the smooth muscle of blood vessels and when stimulated, cause vasoconstriction, which increases blood pressure. While alpha-1 receptors do affect the cardiovascular system, they do not directly influence heart rate or myocardial contractility.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
A) Pupil constriction: Pupil constriction (miosis) is primarily mediated by the parasympathetic nervous system through muscarinic receptors, not nicotinic receptors. Nicotinic receptors, when stimulated, affect skeletal muscle contraction, not the size of the pupils.
B) Muscle contraction: Nicotinic receptors are located on skeletal muscle cells and are responsible for mediating muscle contraction when activated. When a drug stimulates nicotinic receptors, the expected outcome is muscle contraction, as these receptors play a critical role in neuromuscular transmission.
C) Increase GI motility: While nicotinic receptors are involved in muscle contraction, they are not the primary mediators of gastrointestinal motility. Muscarinic receptors, which are part of the parasympathetic nervous system, primarily control GI motility. Stimulating muscarinic receptors would lead to increased motility, but not nicotinic receptors.
D) Decrease in heart rate: A decrease in heart rate is typically associated with the stimulation of muscarinic receptors, particularly those that influence the parasympathetic nervous system (vagal tone). Nicotinic receptor activation does not directly influence heart rate; in fact, their stimulation is more related to skeletal muscle contraction.
Correct Answer is B
Explanation
A) Pupil dilation:
Pupil dilation is typically a response from stimulation of the sympathetic nervous system, not the parasympathetic system. The parasympathetic system tends to cause pupil constriction, so pupil dilation would not be an expected response to a parasympathetic agonist.
B) Increased gastrointestinal motility:
Stimulation of the parasympathetic nervous system, which is responsible for the "rest and digest" response, promotes the movement of food through the digestive tract, increasing gastrointestinal motility. This response is a classic sign that the parasympathetic system is being activated. Drugs that stimulate the parasympathetic nervous system often aim to enhance digestive functions.
C) Vasoconstriction:
Vasoconstriction is typically mediated by the sympathetic nervous system, not the parasympathetic system. The sympathetic nervous system activates alpha-adrenergic receptors that cause blood vessels to constrict, raising blood pressure. The parasympathetic system, on the other hand, typically promotes vasodilation, lowering blood pressure.
D) Increased heart rate:
Increased heart rate is generally associated with the sympathetic nervous system, which prepares the body for "fight or flight." The parasympathetic nervous system, in contrast, slows down the heart rate through vagal stimulation, so an increase in heart rate would not be the expected response to parasympathetic stimulation.
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