The nurse is preparing to administer a chewable tablet to a preschool-age child. The child's parent reports always crushing the tablet and mixing it with pudding when giving it at home. What is the nurse's next action?

Ask the pharmacist if the drug may be crushed.

Crush the tablet and mix it with pudding.

Insist that the tablet must be chewed as ordered.

Request a liquid form of the medication from the pharmacy.

Answer and Explanation

The Correct Answer is A

a) The safest action is to consult the pharmacist to determine if the chewable tablet can be crushed without affecting its efficacy or safety. Some chewable tablets must be chewed for proper absorption, while others may be safely crushed.

b) Crushing the tablet without verifying its safety could alter the drug's effectiveness or cause adverse effects, so it should not be done without confirmation.

c) Insisting that the tablet be chewed disregards the child’s potential difficulty with chewing, which may lead to refusal or improper administration.

d) Requesting a liquid form could be an alternative, but it is not the immediate next step. Some medications may not be available in liquid form, so checking with the pharmacist first is the appropriate action.

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Correct Answer is C

Explanation

A. While pediatric doses are often weight-based, this does not fully account for differences in drug metabolism and effects in children. Pediatric drug safety requires specific testing beyond weight comparisons to adults.

B. Relying on repeated use over time to determine safety is not an evidence-based approach. Drug approval for pediatric use requires formal clinical trials to establish safety and efficacy.

C. The U.S. FDA and other regulatory agencies require that drugs intended for pediatric use undergo clinical trials specifically designed to assess safety, efficacy, and appropriate dosing in children. This ensures that medications are appropriately tested before being marketed for pediatric patients.

D. While some post-marketing studies may include children, initial approval for pediatric use requires pre-market clinical testing. Relying solely on post-marketing studies does not ensure comprehensive safety data before widespread pediatric use.

A. None B. 50 mg C. 100 mg D. 200 mg

Correct Answer is C

Explanation

A. The statement that no drug remains is incorrect. A drug with a half-life of 8 hours will not be completely eliminated in 24 hours, as it follows a predictable pattern of reduction.

B. A reduction to 50 mg would require additional half-life intervals beyond 24 hours. The drug concentration decreases by half every 8 hours, meaning it would take more than 24 hours to reach this level.

C. The correct calculation follows the half-life principle:

- At 8 hours: 800 mg → 400 mg

- At 16 hours: 400 mg → 200 mg

- At 24 hours: 200 mg → 100 mg

Therefore, 100 mg of the drug remains after 24 hours.

D. While 200 mg is a step in the process, it represents the amount remaining after only 16 hours, not the full 24-hour period.

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The nurse is preparing to administer a chewable tablet to a preschool-age child. The child's parent reports always crushing the tablet and mixing it with pudding when giving it at home. What is the nurse's next action?

Nursing Test Bank

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