Which of the following medication classes can be used to treat PUD/GERD? (Select all that apply)
NSAIDs
Antacids
Laxatives
H2 antagonists
Proton pump inhibitors
Correct Answer : B,D,E
Choice A reason: NSAIDs, like ibuprofen, exacerbate peptic ulcer disease (PUD) and gastroesophageal reflux disease (GERD) by inhibiting COX-1, reducing protective gastric mucus and increasing acid-related damage. They are contraindicated in these conditions, making this choice incorrect for treatment.
Choice B reason: Antacids neutralize gastric acid, providing rapid symptom relief in PUD and GERD by reducing acid irritation on the esophagus and stomach lining. They are a standard, non-prescription option for mild symptoms, making this a correct choice for managing these conditions.
Choice C reason: Laxatives treat constipation by promoting bowel movements but have no role in PUD or GERD, which involve acid-related damage to the stomach or esophagus. They don’t affect gastric acid or mucosal protection, making this choice incorrect for treatment.
Choice D reason: H2 antagonists, like ranitidine, reduce gastric acid secretion by blocking histamine receptors on parietal cells, promoting ulcer healing and relieving GERD symptoms. They are a mainstay treatment for both conditions, making this a correct choice for effective management.
Choice E reason: Proton pump inhibitors, like omeprazole, strongly inhibit gastric acid production by blocking the proton pump in parietal cells, allowing ulcer healing and reducing GERD symptoms. They are first-line therapy for PUD and GERD, making this a correct choice.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is D
Explanation
Choice A reason: Pulse oximetry of 95% is near normal and not a major concern for beta agonist administration. Tachycardia is more critical due to cardiac stimulation, so this is incorrect.
Choice B reason: A respiratory rate of 22 is slightly elevated but acceptable in respiratory conditions. Beta agonists target airways, but tachycardia is a greater risk, making this incorrect.
Choice C reason: Blood pressure of 100/60 mm Hg is low, but beta agonists primarily affect heart rate. A pre-existing tachycardia is more concerning contraindication, so this is incorrect.
Choice D reason: A heart rate of 120 beats/min is concerning, as beta agonists increase heart rate, risking arrhythmias. This requires evaluation before administration, making it the correct concern.
Correct Answer is C
Explanation
Choice A reason: Poor medication compliance may worsen heart failure but isn’t directly linked to crackles and shortness of breath. These symptoms result from fluid overload due to reduced cardiac output, not solely non-adherence. This choice is less specific to the physiological cause described.
Choice B reason: Increased ventricular contraction force, as with inotropes like digoxin, improves cardiac output, reducing fluid backup. Crackles and shortness of breath indicate fluid overload from poor heart function, not enhanced contraction, making this choice incorrect for the symptoms’ cause.
Choice C reason: Decreased ventricular contraction force in heart failure reduces cardiac output, causing blood to back up into the lungs, leading to pulmonary edema. This manifests as crackles and shortness of breath due to fluid accumulation, making this the correct physiological explanation for the symptoms.
Choice D reason: Lack of exercise may contribute to overall heart failure progression but doesn’t directly cause crackles and shortness of breath. These symptoms stem from acute fluid overload due to impaired cardiac pumping, not deconditioning, making this choice incorrect for the immediate cause.
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