A new graduate nurse preparing to administer medications knows that which of the following is required for a drug to move through the body?

A transporter shell

Selectivity and effectiveness

The ability to cross membranes

Development of an electric charge

Answer and Explanation

The Correct Answer is C

Choice A reason: A transporter shell is not a pharmacological concept; drugs use transport proteins or diffusion. Membrane crossing is key, so this is incorrect for drug movement.

Choice B reason: Selectivity and effectiveness define therapeutic action, not physical movement. Drugs must cross membranes to reach targets, so this is incorrect.

Choice C reason: Drugs must cross cell membranes to move through the body, affecting absorption and distribution. This is a fundamental requirement, making it the correct choice.

Choice D reason: An electric charge may influence solubility but isn’t required for movement. Membrane permeability is essential, so this is incorrect for drug pharmacokinetics.

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Correct Answer is A

Explanation

Choice A reason: Furosemide, a loop diuretic, reduces blood volume, often lowering blood pressure. Monitoring for hypotension is critical to prevent dizziness or shock, making this the correct manifestation to observe.

Choice B reason: Decreased temperature is not a common effect of furosemide, which primarily affects fluid balance. Blood pressure changes are more relevant, so this is incorrect.

Choice C reason: Furosemide may increase heart rate due to volume loss, not decrease pulse. Hypotension is a primary concern, making this incorrect for the expected manifestation.

Choice D reason: Decreased respiratory rate is unrelated to furosemide, which may improve breathing in heart failure but not slow respiration. Blood pressure is key, so this is incorrect.

A. Enterochromaffin cells B. Beta cells C. Parietal cells D. Mucus cells E. G cells

Correct Answer is ["A","C","E"]

Explanation

Choice A reason: Enterochromaffin-like (ECL) cells release histamine, which stimulates parietal cells to secrete hydrochloric acid via H2 receptors. This increases gastric acid production, critical for digestion, and is a key component in the acid secretion pathway, making this a correct choice for acid-increasing cells.

Choice B reason: Beta cells, located in the pancreas, secrete insulin to regulate glucose, not gastric acid. They have no role in stomach acid production or regulation, which is controlled by gastric cells like parietal or G cells, making this choice incorrect.

Choice C reason: Parietal cells directly secrete hydrochloric acid into the stomach lumen via the H+/K+-ATPase pump, significantly increasing gastric acidity for digestion. Activated by histamine, gastrin, and acetylcholine, they are central to acid production, making this a correct choice for the question.

Choice D reason: Mucus cells secrete protective mucus to shield the stomach lining from acid and pepsin, not acid itself. They reduce damage from acidity but don’t contribute to its production, making this choice incorrect for cells that increase stomach acid.

Choice E reason: G cells secrete gastrin, a hormone that stimulates parietal cells to produce hydrochloric acid. Gastrin enhances acid secretion indirectly by activating parietal cells and ECL cells, playing a key role in gastric acid regulation, making this a correct choice.

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A new graduate nurse preparing to administer medications knows that which of the following is required for a drug to move through the body?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

The nurse should monitor for which potential clinical manifestation after administering furosemide (Lasix)?

Correct Answer is A

Explanation

Which of the following cells increase acid in the stomach? (Select all that apply)

Correct Answer is ["A","C","E"]

Explanation

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