What causes type 1 diabetes mellitus?
Genetic mutations leading to insulin resistance
Excessive oral intake of simple carbohydrates
Pancreatic damage from alcohol consumption
Autoimmune attacks on pancreatic beta cells
The Correct Answer is D
Choice A reason: Genetic mutations causing insulin resistance describe type 2 diabetes. Type 1 diabetes results from autoimmune destruction of beta cells, leading to absolute insulin deficiency, not resistance, making this choice incorrect.
Choice B reason: Excessive carbohydrate intake does not cause type 1 diabetes, which is autoimmune. It may exacerbate hyperglycemia in diabetes but is not the primary cause, making this choice incorrect.
Choice C reason: Pancreatic damage from alcohol can cause pancreatitis, not type 1 diabetes. Type 1 is autoimmune, destroying insulin-producing beta cells, unrelated to alcohol-induced damage, making this choice incorrect.
Choice D reason: Type 1 diabetes is caused by autoimmune destruction of pancreatic beta cells, leading to absolute insulin deficiency. Autoantibodies target beta cells, causing hyperglycemia, making this the correct pathophysiological cause.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Platelet-activating factor promotes platelet aggregation and inflammation but does not directly cause redness. Redness in acute inflammation results from increased blood flow to the affected area, driven by vascular changes, not primarily platelet activity, making this choice incorrect.
Choice B reason: Vasodilation, triggered by inflammatory mediators like histamine, increases blood flow to the inflamed area, causing redness (erythema). Dilated vessels allow more oxygenated blood to reach tissues, a hallmark of acute inflammation, making this the correct pathophysiological process for redness.
Choice C reason: Increased capillary permeability allows fluid and proteins to leak into tissues, causing swelling (edema) in inflammation. While it contributes to inflammation, it does not directly cause redness, which is due to increased blood flow, making this choice incorrect.
Choice D reason: Vasoconstriction reduces blood flow, causing pallor, not redness. In acute inflammation, vasodilation predominates to deliver immune cells and nutrients, while vasoconstriction is an initial transient response, making this choice incorrect for causing redness.
Correct Answer is D
Explanation
Choice A reason: Lack of appetite is not typical in type 1 diabetes, where increased appetite (polyphagia) occurs due to glucose deprivation in cells. Weight loss is more characteristic, making this choice incorrect.
Choice B reason: Oliguria (low urine output) is not a feature of type 1 diabetes, which causes polyuria due to osmotic diuresis from hyperglycemia. This makes the choice incorrect for type 1 diabetes.
Choice C reason: Night sweats are not a primary manifestation of type 1 diabetes. They may occur in hypoglycemia but are not a hallmark symptom, unlike weight loss, making this choice incorrect.
Choice D reason: Weight loss in type 1 diabetes results from insulin deficiency, preventing glucose uptake, leading to fat and muscle breakdown for energy. This is a classic symptom, making this the correct choice.
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