What is the best reason that drug toxicity can occur as a result of an age-related change in the liver?
Rapid blood flow through the liver
Decreased liver enzyme activity
Fluid accumulation in the portal vein
Increased liver size
The Correct Answer is B
A. Rapid blood flow through the liver
Blood flow to the liver actually decreases with age, which may impair drug metabolism, not accelerate it.
B. Decreased liver enzyme activity
Liver enzyme activity declines with age, reducing the liver’s ability to metabolize drugs, increasing the risk for toxicity.
C. Fluid accumulation in the portal vein
This is associated with portal hypertension in liver disease, not a normal age-related change.
D. Increased liver size
The liver tends to decrease in size and mass with age, not increase.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is A
Explanation
A. Alzheimer dementia
MCI is a known risk factor and often a prodromal stage for Alzheimer's disease; many people with MCI progress to Alzheimer's.
B. Dementia, non-Alzheimer type
While possible, the most common progression is to Alzheimer’s, not other forms of dementia.
C. Psychotic disorders
MCI is primarily cognitive and does not typically progress to psychotic disorders.
D. Parkinson disease
MCI is not a precursor to Parkinson's disease, which is a neurodegenerative motor disorder.
Correct Answer is D
Explanation
A. Arthritis
This is a joint disease, not a spinal curvature.
B. Lordosis
This is the inward curvature of the lumbar spine, not thoracic.
C. Scoliosis
This refers to a lateral (sideways) curvature of the spine.
D. Kyphosis
Kyphosis is the outward curvature of the thoracic spine, common in elderly individuals due to osteoporosis and vertebral compression, leading to a stooped posture.
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