Which two components are part of the pathophysiology of thalassemia?
Choose 2 answers.
A polypeptide chain of the Hgb structure is deficient.
A thrombus forms at an area of inflammation.
Hgb synthesis is reduced.
A region of arterial wall bulges.
Correct Answer : A,C
A. A polypeptide chain of the Hgb structure is deficient. Thalassemia is a genetic disorder characterized by a deficiency in one of the polypeptide chains (alpha or beta) that make up hemoglobin (Hgb). This leads to abnormal hemoglobin formation and reduced oxygen-carrying capacity of the blood.
B. A thrombus forms at an area of inflammation. Thrombus formation is related to blood clotting disorders or vascular injury, not to the pathophysiology of thalassemia.
C. Hgb synthesis is reduced. In thalassemia, the synthesis of hemoglobin is reduced due to the defective production of one of its chains, leading to anemia and other complications.
D. A region of arterial wall bulges: This describes an aneurysm, which is unrelated to thalassemia.
E. A high shearing force acts on arterial walls: This is associated with conditions like hypertension or atherosclerosis, not thalassemia.
F. Ventricular contractile function decreases: This is related to heart failure or cardiomyopathy and is not a feature of thalassemia.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","E","F"]
Explanation
A. Severe tantrums: Children with ND-PAE often exhibit severe behavioral issues, including tantrums, due to difficulties with emotional regulation.
B. Frequent nausea: Nausea is not a typical symptom associated with ND-PAE.
C. Difficulty hearing sounds in a crowded room: Children with ND-PAE typically have difficulties with social interactions, mood regulation, and behavior. Whiledifficulty hearing sounds in a crowded roomcan be a challenge for some children, it is not a primary characteristic of ND-PAE. The main issues are more related to behavioral and social difficulties, such as severe tantrums, mood issues, and difficulty playing with other children.
D. Spina bifida: Spina bifida is a neural tube defect and is not directly associated with ND-PAE, although prenatal alcohol exposure can lead to various neurodevelopmental disorders.
E. Mood issues such as irritability: Mood instability, including irritability, is a common issue in children with ND-PAE, often linked to the neurological impact of prenatal alcohol exposure.
F. Difficulty playing with other children: Social difficulties, including challenges in interacting with peers, are often observed in children with ND-PAE due to impaired social cognition and behavior.
Correct Answer is ["A","F"]
Explanation
A. Loss of voluntary movement: Huntington's disease is a neurodegenerative disorder characterized by the progressive loss of voluntary movement, leading to difficulties in performing daily activities.
B. Numbness: Numbness is not typically associated with Huntington's disease, which primarily affects movement and cognitive function.
C. Constipation: While constipation can occur in many conditions, it is not a hallmark symptom of Huntington's disease.
D. Urinary dysfunction: Urinary dysfunction is not a primary symptom of Huntington's disease.
E. Visual dysfunction: Visual dysfunction is not typically associated with Huntington's disease.
F. Dyskinesia: Dyskinesia, or involuntary, erratic movements, is a hallmark symptom of Huntington's disease. It is one of the main motor symptoms observed in affected individuals.
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