Which two components are part of the pathophysiology of thalassemia?
Choose 2 answers.
A polypeptide chain of the Hgb structure is deficient.
A thrombus forms at an area of inflammation.
Hgb synthesis is reduced.
A region of arterial wall bulges.
Correct Answer : A,C
A. A polypeptide chain of the Hgb structure is deficient. Thalassemia is a genetic disorder characterized by a deficiency in one of the polypeptide chains (alpha or beta) that make up hemoglobin (Hgb). This leads to abnormal hemoglobin formation and reduced oxygen-carrying capacity of the blood.
B. A thrombus forms at an area of inflammation. Thrombus formation is related to blood clotting disorders or vascular injury, not to the pathophysiology of thalassemia.
C. Hgb synthesis is reduced. In thalassemia, the synthesis of hemoglobin is reduced due to the defective production of one of its chains, leading to anemia and other complications.
D. A region of arterial wall bulges: This describes an aneurysm, which is unrelated to thalassemia.
E. A high shearing force acts on arterial walls: This is associated with conditions like hypertension or atherosclerosis, not thalassemia.
F. Ventricular contractile function decreases: This is related to heart failure or cardiomyopathy and is not a feature of thalassemia.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Gastrointestinal symptoms such as abdominal pain and diarrhea: These symptoms are not specific to hyponatremia and can be seen in various conditions.
B. Gastrointestinal symptoms such as abdominal pain and constipation: Constipation is not typically associated with hyponatremia.
C. Neurological symptoms such as confusion, irritability, or lethargy: Hyponatremia, which is low sodium levels in the blood, often leads to neurological symptoms like confusion, irritability, lethargy, seizures, and in severe cases, coma, due to the effect of low sodium on brain cells.
D. Neurological symptoms such as numbness and tingling of the hands and feet: Numbness and tingling are more commonly associated with electrolyte imbalances such as hypocalcemia or hypomagnesemia, rather than hyponatremia.
Correct Answer is ["C","D"]
Explanation
A. Oral anticoagulation is a treatment to prevent clots and reduce the risk of ischemic stroke, not a mechanism that causes a clot to form.
B. Anoxic encephalopathy is brain damage due to a lack of oxygen, which can be a result of stroke but is not a cause of thrombus formation.
C. Carotid stenosis or the narrowing of the carotid arteries, can lead to the formation of clots that may travel to the brain and cause an ischemic stroke.
D. Atrial fibrillation is a heart rhythm disorder that can lead to the formation of blood clots in the heart. These clots can then travel to the brain and cause an ischemic stroke.
E. Glutamate toxicity refers to neuronal damage caused by excessive glutamate but is not a mechanism that leads to clot formation or ischemic stroke.
Whether you are a student looking to ace your exams or a practicing nurse seeking to enhance your expertise , our nursing education contents will empower you with the confidence and competence to make a difference in the lives of patients and become a respected leader in the healthcare field.
Visit Naxlex, invest in your future and unlock endless possibilities with our unparalleled nursing education contents today
Report Wrong Answer on the Current Question
Do you disagree with the answer? If yes, what is your expected answer? Explain.
Kindly be descriptive with the issue you are facing.