In DiGeorge disease, what is the cause? (Select all that apply)
Lack of development of the thymus
B cells cannot mature
T cells cannot mature
Lack of development of the bursa
Correct Answer : A,C
Choice A reason: DiGeorge disease involves thymic hypoplasia or aplasia, impairing T-cell development. This is a primary cause, leading to immune deficiency, making it a correct choice for the condition’s etiology.
Choice B reason: B-cell maturation is generally preserved in DiGeorge disease, as it primarily affects T-cells due to thymic defects. T-cell issues are central, so this is incorrect for the cause.
Choice C reason: T cells cannot mature in DiGeorge disease due to thymic underdevelopment, causing severe immunodeficiency. This is a core feature of the syndrome, making it a correct choice for the cause.
Choice D reason: Humans lack a bursa; B-cell maturation occurs in bone marrow. DiGeorge affects the thymus and T-cells, not a nonexistent bursa, so this is incorrect for the cause.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
Choice A reason: Aspirin inhibits TXA2 synthesis, reducing platelet adhesion and clotting. This is a true mechanism of aspirin’s antiplatelet effect, so it’s incorrect as the exception.
Choice B reason: Aspirin reduces prostaglandin production, which decreases platelet aggregation. This is a valid antiplatelet mechanism, so it’s incorrect for the action aspirin does not perform.
Choice C reason: Aspirin does not inhibit fibrinogen-to-fibrin conversion; this is part of the coagulation cascade, not platelet function. Aspirin targets platelets, making this the correct action it doesn’t perform.
Choice D reason: Aspirin inhibits ADP-induced platelet aggregation, minimizing plug formation. This is a true antiplatelet effect, so it’s incorrect as the action aspirin does not do.
Correct Answer is B
Explanation
Choice A reason: Weight loss occurs in both DKA and HHNS due to prolonged hyperglycemia and fluid loss. Kussmaul respirations are specific to DKA’s acidosis, so this is incorrect for DKA-only.
Choice B reason: Kussmaul respirations, rapid and deep breathing, are unique to DKA, compensating for metabolic acidosis from ketones. HHNS lacks significant acidosis, making this the correct DKA-specific manifestation.
Choice C reason: Increased serum glucose is common to both DKA and HHNS, as both involve severe hyperglycemia. Kussmaul respirations are DKA-specific, so this is incorrect.
Choice D reason: Fluid loss occurs in both DKA and HHNS due to osmotic diuresis. Kussmaul respirations are exclusive to DKA’s acidotic state, so this is incorrect.
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