The healthcare provider orders Lovenox 1 mg/kg SQ now. Your patient weighs 198 lbs. The available concentration is Lovenox 30 mg/0.3 mL. How many mL will the patient receive?

0.9 mL

1.2 mL

0.6 mL

0.3 mL

Answer and Explanation

The Correct Answer is A

Choice A reason: Patient weight: 198 lbs ÷ 2.2 = 90 kg. Dose: 1 mg/kg × 90 kg = 90 mg. Volume: 90 mg ÷ (30 mg/0.3 mL) = 90 × 0.3/30 = 0.9 mL. This delivers the correct anticoagulant dose for conditions like DVT, making it the accurate choice.

Choice B reason: For 90 kg (198 lbs ÷ 2.2), the dose is 90 mg. Volume: 90 mg ÷ (30 mg/0.3 mL) = 0.9 mL. Choice B (1.2 mL) delivers 120 mg (1.2 × 30/0.3), overdosing Lovenox, increasing bleeding risk, making it incorrect.

Choice C reason: The correct volume for 90 mg is 0.9 mL (90 ÷ 30 mg/0.3 mL). Choice C (0.6 mL) delivers 60 mg (0.6 × 30/0.3), underdosing Lovenox, reducing anticoagulant efficacy, which could fail to prevent thrombosis, making this choice incorrect.

Choice D reason: For 90 mg, the volume is 0.9 mL. Choice D (0.3 mL) delivers 30 mg (0.3 × 30/0.3), significantly underdosing Lovenox for a 90 kg patient, risking inadequate anticoagulation and thrombotic events, making this choice incorrect.

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Correct Answer is C

Explanation

Choice A reason: A transporter shell is not a pharmacological concept; drugs use transport proteins or diffusion. Membrane crossing is key, so this is incorrect for drug movement.

Choice B reason: Selectivity and effectiveness define therapeutic action, not physical movement. Drugs must cross membranes to reach targets, so this is incorrect.

Choice C reason: Drugs must cross cell membranes to move through the body, affecting absorption and distribution. This is a fundamental requirement, making it the correct choice.

Choice D reason: An electric charge may influence solubility but isn’t required for movement. Membrane permeability is essential, so this is incorrect for drug pharmacokinetics.

A. It increases or decreases the activity of that receptor. B. It alters the receptor to become non-responsive to its usual endogenous molecules. C. It prevents the action of the receptor by altering its response to chemical mediators. D. It gives the receptor a new function.

Correct Answer is A

Explanation

Choice A reason: Drug-receptor binding either activates (agonists) or inhibits (antagonists) receptor activity, altering physiological responses. This is the primary effect, making it the correct choice for receptor interaction.

Choice B reason: Drugs do not permanently alter receptors non-responsive; they modulate activity temporarily. Non-responsiveness may occur with chronic use, but it’s not the primary effect, so this is incorrect.

Choice C reason: Preventing receptor action is specific to antagonists, not all drugs. drugs bind to receptors. Binding broadly affects activity, so this is incorrect for the general effect of receptor binding.

Choice D reason: Drugs do not give receptors new functions; they enhance or block existing ones. ones. Activity modulation is the key effect, making this incorrect for what occurs during binding.

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The healthcare provider orders Lovenox 1 mg/kg SQ now. Your patient weighs 198 lbs. The available concentration is Lovenox 30 mg/0.3 mL. How many mL will the patient receive?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

A new graduate nurse preparing to administer medications knows that which of the following is required for a drug to move through the body?

Correct Answer is C

Explanation

What occurs when a drug binds to a receptor in the body?

Correct Answer is A

Explanation

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A nurse is preparing to administer a medication and learns that it is a nonselective agonist. What does the nurse understand about this drug?

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When administering a central nervous system depressant, the nurse should closely observe for drug toxicity in which patient?

Two nurses are discussing the theories of drug-receptor interaction. Which statements are true regarding the affinity of a drug and for its receptor? (Select all that apply)