The nurse gives medication to a patient with a history of liver disease. The nurse will monitor this patient for

Decreased drug effects.

Increased drug effects.

Decreased therapeutic range.

Increased therapeutic range.

Answer and Explanation

The Correct Answer is B

a) Decreased drug effects are unlikely in liver disease because impaired liver function reduces drug metabolism, leading to higher drug concentrations in the bloodstream.

b) Increased drug effects occur because the liver is responsible for metabolizing many drugs. In liver disease, drug metabolism is slowed, leading to prolonged drug action and potential toxicity.

c) Decreased therapeutic range is not the primary concern. The therapeutic range refers to the safe and effective drug concentration, but liver disease mainly affects drug metabolism and clearance.

d) Increased therapeutic range is incorrect because liver disease does not widen the range of safe drug levels; instead, it increases the risk of drug accumulation and toxicity.

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Correct Answer is B

Explanation

A. Distribution refers to the movement of the drug from the bloodstream into tissues and organs, but it does not explain why only a portion of the medication reaches the tissues.

B. The first-pass effect occurs when an orally administered drug is metabolized by the liver before reaching systemic circulation. Aspirin, when taken orally, undergoes significant metabolism in the liver, reducing the amount of active drug available to exert its therapeutic effect. This explains why only a portion of the drug reaches the tissues.

C. Reduced absorption can limit drug availability, but aspirin is generally well absorbed in the gastrointestinal tract. The primary reason for reduced drug availability in this case is metabolism by the liver, not poor absorption.

D. Gastrointestinal circulation involves the enterohepatic recycling of some drugs, but it does not explain why only a portion of aspirin reaches systemic circulation. The first-pass effect is the primary factor.

A. Do you feel like you take enough medication, too much, or too little? B. Do you take medications safely when you take them? C. Who prescribed these medications? D. What over-the-counter (OTC) medications do you take? E. Do you take any herbs, vitamins, or supplements?

Correct Answer is ["C","D","E"]

Explanation

a. Asking the patient if they feel they are taking enough, too much, or too little medication may not provide the most useful information for assessing medication safety or appropriateness. It is more important to focus on the types of medications being used and any potential interactions.

b. While medication safety is important, asking directly about who prescribed the medications, OTC medications, and supplements is more pertinent in this context to gather complete information about the patient’s medication regimen.

c. Knowing who prescribed the medications is important for understanding the source of the medications and ensuring they are appropriate for the patient’s condition.

d. Asking about over-the-counter (OTC) medications is essential because OTC drugs can interact with prescribed medications and affect the patient's health.

e. Inquiring about herbs, vitamins, and supplements is crucial because these can also interact with prescription medications and affect their efficacy or safety.

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The nurse gives medication to a patient with a history of liver disease. The nurse will monitor this patient for

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Naxlex Comprehensive Predictor Exams

The patient is taking low-dose aspirin daily for his heart. The nurse knows only a portion of the medication taken actually reaches the tissue due to what process?

Correct Answer is B

Explanation

The nurse is conducting an admission assessment on a client. When collecting data related to medications, the nurse asks, "What medications are you currently taking?" After collecting this information, what other questions should the nurse ask? Select all that apply.

Correct Answer is ["C","D","E"]

Explanation

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