The nurse is caring for an older adult patient who is receiving multiple medications. When monitoring this patient for potential drug toxicity, the nurse should review which lab values closely?
Complete blood count and serum glucose levels
Pancreatic enzymes and urinalysis
Serum creatinine and liver function tests (LFTs)
Serum lipids and electrolytes
The Correct Answer is C
A. Complete blood count (CBC) and serum glucose levels are important for overall health monitoring but do not specifically assess drug metabolism or excretion, which are key factors in drug toxicity.
B. Pancreatic enzymes and urinalysis are useful for detecting pancreatic disorders and infections but are not primary indicators of drug toxicity.
C. Serum creatinine and liver function tests (LFTs) are critical for monitoring drug toxicity, especially in older adults. The kidneys and liver are responsible for drug metabolism and excretion. Impaired kidney function, indicated by elevated serum creatinine, can lead to drug accumulation and toxicity. Abnormal LFTs suggest liver dysfunction, which can affect drug metabolism and increase toxicity risk.
D. Serum lipids and electrolytes are important for cardiovascular and metabolic health but do not directly assess drug metabolism or toxicity risk.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is ["A","B","E"]
Explanation
a) The FDA is responsible for overseeing the testing of drugs for harmful effects, including preclinical trials and clinical trials, to ensure that drugs do not cause unsafe side effects.
b) The FDA ensures that drugs have accurate labeling, including correct dosage, potential side effects, contraindications, and proper use.
c) The FDA does not guarantee that a drug will be free from adverse reactions. While they regulate and monitor drugs, adverse reactions can still occur after approval, and it is the responsibility of healthcare professionals and the manufacturer to monitor for these post-marketing.
d) The FDA does not ensure drug affordability; the pricing of drugs is influenced by many factors, including market forces, healthcare policies, and manufacturer decisions.
e) The FDA ensures that drugs are effective by overseeing clinical trials to demonstrate that the drug has the intended therapeutic effects for its indicated use.
Correct Answer is B
Explanation
A. Duration of action refers to the length of time a drug remains effective after reaching the MEC, but it does not describe the time required to reach this threshold.
B. Onset of action is the time it takes for a drug to reach the minimum effective concentration (MEC) and begin producing a therapeutic effect. This is influenced by factors such as drug absorption and distribution.
C. Peak action time refers to the time at which the drug reaches its highest concentration in the bloodstream, not the time required to reach the MEC.
D. The time response curve is a graphical representation of a drug's effects over time but does not specifically define the time needed to reach the MEC.
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