The nurse is providing education about medication management for a client with Paget's disease. Which medication is commonly used as the first-line treatment for this condition?

Bowing of long bones is a characteristic skeletal finding in Paget's disease. The abnormal bone remodeling can lead to bone bowing and misalignment, particularly in the long bones of the arms and legs.

a. Scoliosis: Scoliosis is a lateral curvature of the spine and is not directly associated with Paget's disease. It may be related to other musculoskeletal conditions.

b. Kyphosis: Kyphosis is an excessive forward curvature of the spine, often seen in conditions like osteoporosis, but it is not a primary finding in Paget's disease.

c. Bone tenderness: Bone tenderness may be present due to the bone inflammation and pain associated with Paget's disease, but it is not a specific skeletal finding.

The bone pain experienced by clients with Paget's disease is often due to microfractures and inflammation in the affected bones. The increased bone turnover and remodeling lead to weaker bones, making them more susceptible to microfractures. The inflammation at the site of these microfractures contributes to the pain, which worsens with activity.

a. Decreased blood flow to bones: Paget's disease does not typically cause decreased blood flow to bones. Instead, the condition leads to increased vascularity in affected bones.

b. Bone infarction: Bone infarction (death of bone tissue due to inadequate blood supply) is not a characteristic feature of Paget's disease. Microfractures and inflammation are more common causes of bone pain in this condition.

d. Compression of nerve roots: While nerve compression can cause bone pain, it is not a primary mechanism of pain in Paget's disease. The pain is primarily related to bone remodeling and inflammation.