The nurse is providing education about medication management for a client with Paget's disease. Which medication is commonly used as the first-line treatment for this condition?

A potential complication of Paget's disease is an increased risk of fractures. The abnormal bone remodeling and weakening of bone structures in Paget's disease can lead to an increased susceptibility to fractures.

a. Hypertension: Hypertension is not a direct complication of Paget's disease. The condition primarily affects bone structures.

b. Osteoporosis: Paget's disease is not a form of osteoporosis. While both conditions involve bone changes, they have distinct pathophysiological mechanisms.

d. Type 2 diabetes mellitus: Type 2 diabetes mellitus is not a complication of Paget's disease. The conditions are unrelated and have different underlying causes.

Bisphosphonates are commonly used as the first-line treatment for Paget's disease. They work by slowing down bone resorption and promoting more balanced bone remodeling, helping to control the excessive bone turnover characteristic of the condition.

a. Calcium supplements: While calcium supplements are essential for overall bone health, they are not the first-line treatment for Paget's disease. Bisphosphonates specifically target the abnormal bone remodeling associated with the condition.

b. Nonsteroidal anti-inflammatory drugs (NSAIDs): NSAIDs may help manage pain and inflammation associated with Paget's disease, but they do not directly address the underlying bone remodeling abnormalities. Bisphosphonates are more effective in treating the condition.

d. Vitamin D supplements: Vitamin D is necessary for calcium absorption and bone health, but it is not the primary treatment for Paget's disease. Bisphosphonates are the mainstay of therapy.