When the blood becomes acidic (acidosis) and bicarbonate ions have been depleted, new bicarbonate ions must be generated in the plasma. Which of the following is NOT a means for replenishing bicarbonate ions?
Buffered hydrogen ions are excreted in urine.
Glutamine is metabolized by deamination, oxidation, and acidification.
Ammonium ions are excreted in urine.
Bicarbonate ions are reclaimed by tubular reabsorption.
The Correct Answer is D
A. Buffered hydrogen ions are excreted in urine: This process allows new bicarbonate ions to enter the plasma, helping correct acidosis.
B. Glutamine is metabolized by deamination, oxidation, and acidification: Glutamine metabolism in renal tubule cells generates ammonia and bicarbonate, contributing to acid-base balance.
C. Ammonium ions are excreted in urine: Excreting ammonium (NH₄⁺) removes H⁺ from the body and indirectly adds new bicarbonate to the plasma.
D. Bicarbonate ions are reclaimed by tubular reabsorption: This does not generate new bicarbonate-it simply prevents loss of existing bicarbonate, which is important but not a replenishing mechanism during depletion.
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Related Questions
Correct Answer is B
Explanation
A. It increases both Na⁺ and K⁺ reabsorption. It increases both Na⁺ and K⁺ secretion: This contradicts the actual function. Aldosterone causes Na⁺ reabsorption and K⁺ secretion, not reabsorption of both.
B. It increases Na⁺ reabsorption and K⁺ secretion: Aldosterone acts on the distal tubules and collecting ducts of the nephron, causing sodium reabsorption (to increase blood volume/pressure) and potassium excretion.
C. It reduces Na⁺ reabsorption and K⁺ secretion: This is the opposite of aldosterone's action.
D. It causes the urine to be more diluted: Aldosterone causes sodium (and water) retention, leading to concentrated urine. Dilution of urine is more associated with ADH inhibition.
Correct Answer is B
Explanation
A. Terminal sulcus: This is a V-shaped groove on the tongue that marks the division between the anterior and posterior tongue-not related to tongue mobility.
B. Lingual frenulum: This is a fold of mucous membrane under the tongue that may be too short or tight in some children (ankyloglossia or “tongue-tie”), limiting movement. Surgery may involve cutting this to free the tongue.
C. Uvula: The uvula is part of the soft palate and plays a role in speech and swallowing, not tongue movement.
D. Palatine tonsils: These are lymphatic tissues in the oropharynx and have no role in tongue movement.
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