Which conditions are common progressive neurodegenerative disorders?

A. Ovarian tumor:

The symptoms (chronic pelvic pain, abdominal girth, fever, vomiting, and an elevated HE4 test) are suggestive of an ovarian tumor or potentially ovarian cancer, which may require surgical intervention like a salpingo-oophorectomy (removal of the ovary and fallopian tube).

B. Pelvic inflammatory disease (PID):

PID typically causes pelvic pain and fever, but the increased abdominal girth and elevated HE4 test make an ovarian tumor more likely.

C. Dysmenorrhea:

Dysmenorrhea refers to painful menstruation, which typically doesn't present with the severe symptoms described here, such as fever, vomiting, and abdominal girth changes.

D. Benign fibroadenoma:

Fibroadenomas are benign breast tumors, not related to the ovaries or the symptoms presented.

A. There is no known safe level of alcohol use during pregnancy or when trying to get pregnant:

Research has shown that any alcohol consumption during pregnancy can potentially cause fetal alcohol spectrum disorders (FASD). There is no safe amount.

B. Alcohol prior to conception cannot impact the fetus:

Alcohol use prior to conception can affect fertility and early embryonic development, especially since many pregnancies are unrecognized during early stages.

C. Alcohol exposure is most dangerous during the last trimester:

All trimesters are critical, but the first trimester is often considered the most vulnerable for teratogenic effects, especially for organ formation.

D. Fetal alcohol exposure increases the likelihood of twins or other multiples:

Alcohol exposure does not increase the likelihood of multiple births; it causes developmental abnormalities.