A nurse is assessing a client with anemia, and the client reports a history of chronic alcoholism. Which type of anemia is most likely to be associated with alcoholism?

A) This choice is incorrect because hemolytic anemia typically presents with normocytic and normochromic red blood cells, as the bone marrow compensates by releasing immature red blood cells.

B) This choice is incorrect because sickle cell anemia is characterized by the presence of sickle-shaped red blood cells and is not associated with microcytic and hypochromic cells.

C) This choice is correct. Thalassemia is a type of anemia in which the synthesis of globin chains is impaired, leading to microcytic and hypochromic red blood cells.

D) This choice is incorrect because pernicious anemia is associated with macrocytic and normochromic red blood cells due to vitamin B12 deficiency.

A) This choice is incorrect because ESA therapy is not typically associated with hypotension. In fact, an increase in blood pressure is a potential side effect of ESAs.

B) This choice is incorrect because hypokalemia (low potassium levels) is not a common adverse effect of ESA therapy.

C) This choice is incorrect because hypoglycemia (low blood sugar) is not a typical side effect of ESA therapy.

D) This choice is correct. ESA therapy can increase the risk of thrombosis (blood clot formation) due to the stimulation of red blood cell production. Clients receiving ESAs should be monitored for signs of thrombosis, such as swelling, pain, and redness in the extremities.