A nurse is assessing the patient's home medication use. After listening to the patient list current medications, the nurse asks what priority question?

Do you take any generic medications?

Are any of these medications orphan drugs?

Are these medications safe to take during pregnancy?

Do you take any over-the-counter medications?

Answer and Explanation

The Correct Answer is D

a) While knowing if the patient takes generic medications is useful, it is not the priority. Generic and brand-name drugs generally have the same active ingredients and effects.

b) Orphan drugs are used to treat rare diseases, but this is not a primary concern for most patients and does not directly impact medication safety in routine assessments.

c) Asking about medication safety during pregnancy is important if the patient is pregnant or could become pregnant, but it is not the primary concern for all patients.

d) Over-the-counter (OTC) medications can interact with prescribed medications, potentially leading to adverse effects or reduced efficacy. It is crucial to assess OTC use to ensure there are no dangerous drug interactions.

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Correct Answer is A

Explanation

a) Phase III clinical trials involve large groups of human participants and focus on confirming the drug's effectiveness and monitoring for adverse effects. The nurse plays a key role in observing and documenting any side effects experienced by the patients.

b) Working with animals is part of preclinical trials, not phase III studies. By the time a drug reaches phase III, it has already undergone animal testing.

c) While data collected in phase III trials contribute to determining a drug’s effectiveness, the decision-making is primarily done by researchers and regulatory agencies, not individual nurses.

d) Selection of appropriate clients for a drug study is generally determined by researchers and trial coordinators based on inclusion and exclusion criteria, rather than by nurses directly.

A. Healthy and ill subjects B. Subjects with other diseases C. Subjects with disease the drug will treat D. Healthy subjects

Correct Answer is C

Explanation

A. Phase I trials focus on healthy individuals, but the next phase (Phase II) involves patients with the target disease. Including both healthy and ill subjects at this stage is not appropriate.

B. Subjects with other diseases are not included in Phase II trials because the goal is to test the drug in individuals who have the specific condition the drug is intended to treat.

C. Phase II clinical trials focus on evaluating the drug’s efficacy and safety in individuals who have the disease it is designed to treat. This phase helps determine the optimal dosage and potential side effects in the target population.

D. Healthy subjects are included in Phase I trials to assess safety and pharmacokinetics, but in the next phase (Phase II), the study shifts to testing the drug in patients with the disease it is meant to treat.

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A nurse is assessing the patient's home medication use. After listening to the patient list current medications, the nurse asks what priority question?

Nursing Test Bank

Naxlex Comprehensive Predictor Exams

When involved in phase III drug evaluation studies, which responsibilities would the nurse have?

Correct Answer is A

Explanation

A clinical drug trial is conducting a study of pharmacokinetics and safety of a drug in healthy individuals. The nurse will assist enrollment of participants into the next phase of the study and will include which subject?

Correct Answer is C

Explanation

The nurse is caring for an older adult patient who is receiving multiple medications. When monitoring this patient for potential drug toxicity, the nurse should review which lab values closely?

Which law(s) govern all drug administration by nurses?

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In response to the patient's question about how to know whether drugs are safe, the nurse explains that all medications undergo rigorous scientific testing controlled by what organization?