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Older adults generally mount lower immune responses to vaccines. Which age-related change is likely to contribute to these lower immune responses?

A.

Lower number of complement proteins

B.

Decreased populations of naïve T cells

C.

Impaired primary defenses

D.

Insufficient time outdoors

Answer and Explanation

The Correct Answer is B

Naïve T cells are a type of white blood cell that has not encountered a specific antigen before and are ready to respond to new infections. As people age, the number of naïve T cells decreases due to the shrinking of the thymus gland, which produces and matures T cells. This reduces the ability of the immune system to recognize and fight new pathogens and lowers the effectiveness of vaccines.


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Related Questions

Correct Answer is {"A":{"answers":"A,B"},"B":{"answers":"B"},"C":{"answers":"B"},"D":{"answers":"A"},"E":{"answers":"A"},"F":{"answers":"A,B"}}

Explanation

a. Hemiparesis: Both

  1. Higher fatality rate: Hemorrhagic CVA
  2. Rupture of vessel: Hemorrhagic CVA
  3. Loss of blood flow: Ischemic CVA
  4. Most common: Ischemic CVA
  5. Altered sensorium: Both

Rationale: A cerebrovascular accident (CVA), or stroke, is a sudden interruption of blood supply to the brain, resulting in neurological damage. There are two main types of stroke: ischemic and hemorrhagic. Ischemic stroke occurs when a blood clot or plaque blocks an artery that supplies blood to the brain, causing tissue death due to lack of oxygen and nutrients. Hemorrhagic stroke occurs when a blood vessel in the brain ruptures, causing bleeding into the brain tissue or the surrounding space. Both types of stroke can cause hemiparesis (weakness on one side of the body), altered sensorium (changes in consciousness, alertness, or orientation), and other neurological deficits depending on the location and extent of the damage. However, hemorrhagic stroke has a higher fatality rate than ischemic stroke because of the increased risk of intracranial pressure, cerebral edema, and brain herniation. Ischemic stroke is more common than hemorrhagic stroke, accounting for about 87% of all strokes.

Correct Answer is D

Explanation

Diabetes insipidus is a disorder of water balance caused by a deficiency of antidiuretic hormone (ADH) or a resistance to its action. ADH regulates the reabsorption of water in the kidneys and prevents excessive urine output. Without enough ADH or with reduced sensitivity to it, the kidneys produce large amounts of diluted urine, leading to frequent urination and thirst. Chronic fatigue and mild confusion may result from dehydration and electrolyte imbalance. Serum glucose is not affected by diabetes insipidus, unlike diabetes mellitus, which is a disorder of carbohydrate metabolism.

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