The TNM (Tumor size, Node (lymph) & Metastases) classification is not used for brain tumors for:
Most patients with CNS tumors develop metastatic disease
Brain tumors are more deadly
Tumor size is less relevant than the location and histology
Brain tumors have poor prognosis
The Correct Answer is C
Choice A reason: Most patients with CNS tumors do not develop metastatic disease. Central nervous system (CNS) tumors, including brain tumors, typically do not metastasize outside the CNS. Instead, they grow and exert pressure on adjacent brain structures, leading to neurological symptoms.
Choice B reason: While brain tumors can be very deadly, the TNM classification system is not avoided due to the lethality of the tumors. The main reason for not using the TNM system is because the classification criteria do not align well with the unique aspects of brain tumors.
Choice C reason: Tumor size is less relevant than the location and histology for brain tumors. The location of the tumor within the brain and its histological characteristics (e.g., type, grade, and molecular features) are more critical for prognosis and treatment planning. Brain tumors can cause significant clinical issues even when small, depending on their location.
Choice D reason: Brain tumors can have a poor prognosis, but this is not the reason the TNM classification is not used. The classification system's limitation is primarily due to the fact that brain tumors' behavior and treatment considerations depend more on their location and histological features than on tumor size, nodal involvement, and metastasis, which are the focus of the TNM system.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Oral hypoglycemic drugs are not used as insulin replacements. Insulin replacement is usually achieved through the administration of insulin injections or insulin pumps. These devices deliver the hormone directly into the body to help regulate blood sugar levels, especially in individuals with type 1 diabetes or severe type 2 diabetes where insulin production is significantly impaired. Oral hypoglycemic drugs, on the other hand, work by different mechanisms and are primarily used for type 2 diabetes management.
Choice B reason: Many oral hypoglycemic drugs, such as metformin and thiazolidinediones, work by reducing insulin resistance. Insulin resistance is a condition where the body's cells do not respond effectively to insulin, leading to elevated blood sugar levels. By improving the body's sensitivity to insulin, these drugs help lower blood sugar levels and improve glucose uptake by the cells. This mechanism is crucial for managing type 2 diabetes, where insulin resistance is a significant issue.
Choice C reason: Some oral hypoglycemic drugs, like metformin, do help in reducing glucose production by the liver. However, saying that these drugs "prevent" the formation of glucose is not entirely accurate. These drugs can inhibit gluconeogenesis, the process by which the liver produces glucose, thereby helping to lower blood sugar levels. However, this is only one aspect of their action, and they are not solely classified based on this mechanism.
Choice D reason: Decreasing the body's need for glucose in body cells is not a primary action of oral hypoglycemic drugs. These medications aim to regulate blood glucose levels by improving insulin sensitivity, reducing glucose production in the liver, and sometimes increasing insulin secretion by the pancreas. The goal is to ensure that glucose is effectively utilized by the body's cells and that blood sugar levels are kept within a healthy range.
Correct Answer is D
Explanation
Choice A reason: While certain medications can affect bladder control, they are not the primary cause of stress incontinence. Stress incontinence is specifically related to physical exertion and increased pressure on the bladder, leading to involuntary urine leakage.
Choice B reason: Hypertension, or high blood pressure, is not a direct cause of stress incontinence. Stress incontinence is related to the weakening of pelvic floor muscles and increased intra-abdominal pressure rather than blood pressure levels.
Choice C reason: A full bladder can increase the likelihood of urine leakage in individuals with stress incontinence, but it is not the underlying cause. Stress incontinence occurs due to weakened pelvic floor muscles and increased pressure during physical activities.
Choice D reason: Stress incontinence occurs due to exertional stimuli that increase intra-abdominal pressure, such as coughing, sneezing, laughing, or physical exercise. These activities cause a sudden increase in pressure on the bladder, leading to involuntary urine leakage. The condition is often associated with weakened pelvic floor muscles, which can result from factors such as childbirth, aging, or pelvic surgery.
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