The TNM (Tumor size, Node (lymph) & Metastases) classification is not used for brain tumors for:
Most patients with CNS tumors develop metastatic disease
Brain tumors are more deadly
Tumor size is less relevant than the location and histology
Brain tumors have poor prognosis
The Correct Answer is C
Choice A reason: Most patients with CNS tumors do not develop metastatic disease. Central nervous system (CNS) tumors, including brain tumors, typically do not metastasize outside the CNS. Instead, they grow and exert pressure on adjacent brain structures, leading to neurological symptoms.
Choice B reason: While brain tumors can be very deadly, the TNM classification system is not avoided due to the lethality of the tumors. The main reason for not using the TNM system is because the classification criteria do not align well with the unique aspects of brain tumors.
Choice C reason: Tumor size is less relevant than the location and histology for brain tumors. The location of the tumor within the brain and its histological characteristics (e.g., type, grade, and molecular features) are more critical for prognosis and treatment planning. Brain tumors can cause significant clinical issues even when small, depending on their location.
Choice D reason: Brain tumors can have a poor prognosis, but this is not the reason the TNM classification is not used. The classification system's limitation is primarily due to the fact that brain tumors' behavior and treatment considerations depend more on their location and histological features than on tumor size, nodal involvement, and metastasis, which are the focus of the TNM system.
Nursing Test Bank
Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is B
Explanation
Choice A reason: Alpha cells of the pancreas do not produce insulin. Insulin is produced by the beta cells of the pancreas. Therefore, the absence of alpha cells would not affect insulin secretion.
Choice B reason: The primary function of alpha cells in the pancreas is to produce and secrete glucagon. Glucagon is a hormone that raises blood glucose levels by promoting the conversion of glycogen to glucose in the liver. Without alpha cells, the body would not be able to secrete glucagon, leading to issues with glucose regulation.
Choice C reason: Somatostatin and gastrin are not secreted by alpha cells. Somatostatin is produced by delta cells of the pancreas and other parts of the digestive system, while gastrin is primarily produced by G cells in the stomach lining. Therefore, the absence of alpha cells would not affect the secretion of somatostatin and gastrin.
Choice D reason: Pancreatic polypeptides are produced by PP cells (pancreatic polypeptide cells) in the pancreas. The absence of alpha cells would not impact the secretion of pancreatic polypeptides.
Correct Answer is D
Explanation
Choice A reason: Decreased fluid intake would typically result in lower urine output and higher urine concentration, but it does not directly explain a urine sodium concentration of 10 mmol/L.
Choice B reason: Increased fluid intake would generally lead to higher urine output and lower urine sodium concentration, as the kidneys excrete excess sodium. Therefore, this is not consistent with a urine sodium concentration of 10 mmol/L.
Choice C reason: Insensible loss refers to fluid loss that is not easily measured, such as through sweating or breathing. It does not directly explain the urine sodium concentration.
Choice D reason: Sodium retention is consistent with a low urine sodium concentration of 10 mmol/L in patients with large-volume ascites. In conditions like cirrhosis, the body retains sodium, leading to fluid accumulation in the abdomen (ascites) and lower sodium excretion in the urine.
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