Which of the following statements best describes the difference between the intrinsic and extrinsic controls of the kidney?
Extrinsic controls will reduce blood plasma volume while intrinsic controls will increase blood plasma volumes.
Intrinsic controls raise blood pressure while extrinsic controls lower blood pressure.
Extrinsic and intrinsic controls work in nearly opposite ways.
Extrinsic controls have the greatest effect on systemic blood pressure while intrinsic controls have a greater effect on GFR.
The Correct Answer is D
A. Extrinsic controls will reduce blood plasma volume while intrinsic controls will increase blood plasma volumes: This is too simplistic. Both can influence fluid volume, but their primary goals differ.
B. Intrinsic controls raise blood pressure while extrinsic controls lower blood pressure: Intrinsic controls maintain GFR, not blood pressure; extrinsic controls (like RAAS and sympathetic input) raise BP.
C. Extrinsic and intrinsic controls work in nearly opposite ways: They serve different purposes rather than being true opposites.
D. Extrinsic controls have the greatest effect on systemic blood pressure while intrinsic controls have a greater effect on GFR: Intrinsic (renal autoregulation) maintains a constant GFR; extrinsic controls (like sympathetic nervous system and RAAS) maintain systemic blood pressure, especially during stress or blood loss.
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Naxlex Comprehensive Predictor Exams
Related Questions
Correct Answer is C
Explanation
A. Involves hypothalamic osmoreceptor detection of ion concentration: Osmoreceptors detect osmolarity (solute concentration), not specifically sodium regulation.
B. Is due to specific sodium receptors in the hypothalamus: There are no specific sodium receptors; sodium regulation is largely hormonal.
C. Is linked to blood pressure: Sodium levels affect blood volume and pressure through water retention. The renin-angiotensin-aldosterone system (RAAS) helps regulate both sodium and blood pressure.
D. Involves aldosterone, a hormone that increases sodium excretion in the kidneys: Aldosterone increases sodium reabsorption, not excretion.
Correct Answer is A
Explanation
A. Potassium ion concentration in extracellular fluid: High levels of extracellular potassium stimulate aldosterone secretion and enhance potassium secretion into the renal tubules for excretion. This is the most direct and critical factor.
B. Intracellular sodium levels: While sodium levels affect membrane potentials, they do not directly regulate potassium secretion.
C. The pH of the intracellular fluid: pH changes can influence potassium distribution between compartments but are not the main driver of secretion.
D. The potassium ion content in the renal tubule cells: This reflects storage, not the signal for secretion. The extracellular fluid concentration is what regulates the process.
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