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Choice A is wrong because PT stands for prothrombin time, which is a test that measures the extrinsic pathway of coagulation and the effect of warfarin, a vitamin K antagonist. PT is not affected by bivalirudin.

Choice B is wrong because INR stands for international normalized ratio, which is a standardized way of reporting PT results and the effect of warfarin. INR is also not affected by bivalirudin.

Choice C is wrong because aPTT stands for activated partial thromboplastin time, which is a test that measures the intrinsic pathway of coagulation and the effect of heparin, an indirect thrombin inhibitor. aPTT can be used to monitor bivalirudin therapy, but it is less sensitive and specific than ECT.

Choice A is wrong because avoiding alcohol while taking argatroban is a correct statement. Alcohol can also increase the risk of bleeding and should be avoided or limited by the client.

Choice C is wrong because notifying the dentist that the client is taking argatroban is a correct statement. The client should inform their dentist and other health care providers about their medication history before any invasive procedures, as they may need to adjust or stop their argatroban dose to prevent excessive bleeding.

Choice D is wrong because checking the blood pressure regularly at home is a correct statement. The client should monitor their blood pressure and other signs of bleeding, such as bruising, nosebleeds, blood in urine or stool, or prolonged bleeding from cuts or wounds. The client should also report any symptoms of thrombosis, such as chest pain, shortness of breath, leg pain or swelling, or stroke-like symptoms.

Choice A is wrong because flushing the IV line with heparin before and after giving lepirudin can increase the risk of bleeding and worsening HIT. Heparin is the cause of HIT and should be avoided in patients with this condition.

Choice C is wrong because administering lepirudin as a bolus injection over 15 seconds can result in a rapid and excessive anticoagulation effect, which can increase the risk of bleeding and hemorrhage. Lepirudin should be given as a bolus injection over 15-20 minutes, followed by a continuous infusion.

Choice D is wrong because monitoring the client’s platelet count daily is not sufficient to assess the efficacy and safety of lepirudin therapy. The platelet count is not affected by lepirudin and does not reflect its anticoagulant activity. The aPTT should be monitored at least once daily and more frequently in patients with renal impairment or increased bleeding risk. The normal platelet count range is 150,000 to 450,000 platelets per microliter of blood.

Vitamin K is wrong because it is not an antidote for dabigatran.Vitamin K is used to reverse the effect of warfarin, a vitamin K antagonist that inhibits the synthesis of clotting factors.

Protamine sulfate is wrong because it is not an antidote for dabigatran.Protamine sulfate is used to reverse the effect of heparin, an indirect thrombin inhibitor that enhances the activity of antithrombin.

Aminocaproic acid is wrong because it is not an antidote for dabigatran.Aminocaproic acid is used to treat bleeding caused by excessive fibrinolysis, such as in hemophilia or after surgery.